Clinical trials in United States
Explore clinical trials recruiting across the United States for a wide range of conditions.
Clinical research in United States
The United States runs more clinical trials than any other country, with tens of thousands of studies recruiting at any given time. Research takes place at academic medical centres, hospitals, community clinics and dedicated research sites in every state, covering the full spectrum from first-in-human studies to large phase 3 trials.
Trials of new medicines are conducted under the oversight of the Food and Drug Administration, which reviews investigational new drug applications before human studies can begin. Every trial must also be approved and monitored by an Institutional Review Board, an independent committee that protects the rights and welfare of participants.
Study-related care is generally provided at no cost to participants, and many trials reimburse travel or offer stipends. If you have health insurance, the research team will explain during informed consent what the study covers and what, if anything, is billed to insurance.
How trials are run in United States
Regulator
The Food and Drug Administration (FDA) reviews new medicines before and during clinical research.
Ethics oversight
Institutional Review Boards (IRBs) independently approve and monitor every study.
Research strengths
The world's largest trial ecosystem: oncology, neurology, immunology, rare disease and much more.
Find a clinical trial in United States
Search studies by condition and location on our trial search platform. Searching and enquiring is free for patients.
Clinical trial questions in United States
Usually not. Study drugs, procedures and visits are generally provided at no cost by the trial sponsor. If routine care is billed to insurance, the research team will explain exactly what is covered during informed consent before you agree to anything.
Many US trials offer stipends or reimburse travel, meals and time. Amounts vary widely by study and phase, and any payment must be approved by the trial's Institutional Review Board so it is fair rather than coercive.
The Food and Drug Administration (FDA) reviews investigational new drug applications before human studies begin, and an independent Institutional Review Board (IRB) must approve and monitor every trial to protect participants' rights and welfare.
Search studies by condition and location on Clinrol and send an enquiry. A study coordinator will pre-screen you, explain the protocol and guide you through informed consent before any study procedures start.
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The information on this page has been compiled from various sources and is provided for general informational purposes only. It may not be complete, current or applicable to your circumstances. It is not medical, legal or other professional advice and should not be relied upon as a substitute for professional guidance. Consider your individual circumstances and risks, review the relevant official sources, and speak with your doctor or another appropriately qualified professional before making health-related decisions.